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Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience
INTRODUCTION: The aim of this study was to describe peri-procedural antithrombotic use in patients undergoing transcatheter aortic valve replacement (TAVR) at a single academic medical center. METHODS: Retrospective collection of antiplatelet and anticoagulant use during the index hospitalization fo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675746/ https://www.ncbi.nlm.nih.gov/pubmed/26399647 http://dx.doi.org/10.1007/s40119-015-0050-2 |
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author | Rossi, Jeffrey E. Noll, Andrew Bergmark, Brian McCabe, James M. Nemer, David Okada, David R. Vasudevan, Anant Davidson, Michael Welt, Frederick Eisenhauer, Andrew Shah, Pinak Giugliano, Robert |
author_facet | Rossi, Jeffrey E. Noll, Andrew Bergmark, Brian McCabe, James M. Nemer, David Okada, David R. Vasudevan, Anant Davidson, Michael Welt, Frederick Eisenhauer, Andrew Shah, Pinak Giugliano, Robert |
author_sort | Rossi, Jeffrey E. |
collection | PubMed |
description | INTRODUCTION: The aim of this study was to describe peri-procedural antithrombotic use in patients undergoing transcatheter aortic valve replacement (TAVR) at a single academic medical center. METHODS: Retrospective collection of antiplatelet and anticoagulant use during the index hospitalization for all patients undergoing TAVR at our institution from April 2009 through March 2014. RESULTS: Of a total of 255 patients undergoing the procedure, 132 (51%) had an indication for anticoagulation pre-TAVR and 92 (70% of those with an indication) were on treatment. On discharge, 106 patients (44% of total surviving to discharge, 73% of those surviving with an indication for anticoagulation) were treated with oral anticoagulation. Of these patients, 89 (84%) were discharged on aspirin and an oral anticoagulant without clopidogrel. Only 122 (51% of total patients) were discharged on the regimen of aspirin and clopidogrel alone. CONCLUSION: Peri-procedural antithrombotic regimens vary greatly following TAVR. More than half of patients have an indication for anticoagulation following the procedure. Most patients at our institution who require anticoagulation are discharged on aspirin and an oral anticoagulant, though the optimal regimen requires further investigation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s40119-015-0050-2) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4675746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-46757462015-12-18 Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience Rossi, Jeffrey E. Noll, Andrew Bergmark, Brian McCabe, James M. Nemer, David Okada, David R. Vasudevan, Anant Davidson, Michael Welt, Frederick Eisenhauer, Andrew Shah, Pinak Giugliano, Robert Cardiol Ther Brief Report INTRODUCTION: The aim of this study was to describe peri-procedural antithrombotic use in patients undergoing transcatheter aortic valve replacement (TAVR) at a single academic medical center. METHODS: Retrospective collection of antiplatelet and anticoagulant use during the index hospitalization for all patients undergoing TAVR at our institution from April 2009 through March 2014. RESULTS: Of a total of 255 patients undergoing the procedure, 132 (51%) had an indication for anticoagulation pre-TAVR and 92 (70% of those with an indication) were on treatment. On discharge, 106 patients (44% of total surviving to discharge, 73% of those surviving with an indication for anticoagulation) were treated with oral anticoagulation. Of these patients, 89 (84%) were discharged on aspirin and an oral anticoagulant without clopidogrel. Only 122 (51% of total patients) were discharged on the regimen of aspirin and clopidogrel alone. CONCLUSION: Peri-procedural antithrombotic regimens vary greatly following TAVR. More than half of patients have an indication for anticoagulation following the procedure. Most patients at our institution who require anticoagulation are discharged on aspirin and an oral anticoagulant, though the optimal regimen requires further investigation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s40119-015-0050-2) contains supplementary material, which is available to authorized users. Springer Healthcare 2015-09-23 2015-12 /pmc/articles/PMC4675746/ /pubmed/26399647 http://dx.doi.org/10.1007/s40119-015-0050-2 Text en © The Author(s) 2015 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Brief Report Rossi, Jeffrey E. Noll, Andrew Bergmark, Brian McCabe, James M. Nemer, David Okada, David R. Vasudevan, Anant Davidson, Michael Welt, Frederick Eisenhauer, Andrew Shah, Pinak Giugliano, Robert Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience |
title | Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience |
title_full | Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience |
title_fullStr | Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience |
title_full_unstemmed | Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience |
title_short | Variability in Antithrombotic Therapy Regimens Peri-TAVR: A Single Academic Center Experience |
title_sort | variability in antithrombotic therapy regimens peri-tavr: a single academic center experience |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675746/ https://www.ncbi.nlm.nih.gov/pubmed/26399647 http://dx.doi.org/10.1007/s40119-015-0050-2 |
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