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Optimizing Polymyxin Combinations Against Resistant Gram-Negative Bacteria

Polymyxin combination therapy is increasingly used clinically. However, systematic investigations of such combinations are a relatively recent phenomenon. The emerging pharmacodynamic (PD) and pharmacokinetic (PK) data on CMS/colistin and polymyxin B suggest that caution is required with monotherapy...

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Detalles Bibliográficos
Autores principales:	Bergen, Phillip J., Bulman, Zackery P., Landersdorfer, Cornelia B., Smith, Nicholas, Lenhard, Justin R., Bulitta, Jürgen B., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675771/ https://www.ncbi.nlm.nih.gov/pubmed/26645096 http://dx.doi.org/10.1007/s40121-015-0093-7

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