A predictive signature for therapy assignment and risk assessment in prostate cancer

Prostate cancer remains the second leading cause of death in men. It is imperative to improve patient management in identifying bio-markers for personalized treatment. We demonstrated miR-15/miR-16 loss and miR-21 up-regulation and deregulation of their target genes, which represent a promising sign...

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Detalles Bibliográficos
Autores principales: Bonci, Désirée, De Maria, Ruggero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675789/
https://www.ncbi.nlm.nih.gov/pubmed/26697526
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author Bonci, Désirée
De Maria, Ruggero
author_facet Bonci, Désirée
De Maria, Ruggero
author_sort Bonci, Désirée
collection PubMed
description Prostate cancer remains the second leading cause of death in men. It is imperative to improve patient management in identifying bio-markers for personalized treatment. We demonstrated miR-15/miR-16 loss and miR-21 up-regulation and deregulation of their target genes, which represent a promising signature for ameliorating therapy assignment and risk assessment in prostate cancer.
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spelling pubmed-46757892015-12-22 A predictive signature for therapy assignment and risk assessment in prostate cancer Bonci, Désirée De Maria, Ruggero Oncoscience Research Perspective Prostate cancer remains the second leading cause of death in men. It is imperative to improve patient management in identifying bio-markers for personalized treatment. We demonstrated miR-15/miR-16 loss and miR-21 up-regulation and deregulation of their target genes, which represent a promising signature for ameliorating therapy assignment and risk assessment in prostate cancer. Impact Journals LLC 2015-11-20 /pmc/articles/PMC4675789/ /pubmed/26697526 Text en Copyright: © 2015 Bonci and De Maria http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Perspective
Bonci, Désirée
De Maria, Ruggero
A predictive signature for therapy assignment and risk assessment in prostate cancer
title A predictive signature for therapy assignment and risk assessment in prostate cancer
title_full A predictive signature for therapy assignment and risk assessment in prostate cancer
title_fullStr A predictive signature for therapy assignment and risk assessment in prostate cancer
title_full_unstemmed A predictive signature for therapy assignment and risk assessment in prostate cancer
title_short A predictive signature for therapy assignment and risk assessment in prostate cancer
title_sort predictive signature for therapy assignment and risk assessment in prostate cancer
topic Research Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675789/
https://www.ncbi.nlm.nih.gov/pubmed/26697526
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