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The impact of a human IGF-II analog ([Leu(27)]IGF-II) on fetal growth in a mouse model of fetal growth restriction

Enhancing placental insulin-like growth factor (IGF) availability appears to be an attractive strategy for improving outcomes in fetal growth restriction (FGR). Our approach was the novel use of [Leu(27)]IGF-II, a human IGF-II analog that binds the IGF-II clearance receptor IGF-IIR in fetal growth-r...

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Detalles Bibliográficos
Autores principales:	Charnock, Jayne C., Dilworth, Mark R., Aplin, John D., Sibley, Colin P., Westwood, Melissa, Crocker, Ian P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675800/ https://www.ncbi.nlm.nih.gov/pubmed/26530156 http://dx.doi.org/10.1152/ajpendo.00379.2015

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