Identifying transcription start sites and active enhancer elements using BruUV-seq

BruUV-seq utilizes UV light to introduce transcription-blocking DNA lesions randomly in the genome prior to bromouridine-labeling and deep sequencing of nascent RNA. By inhibiting transcription elongation, but not initiation, pre-treatment with UV light leads to a redistribution of transcription rea...

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Detalles Bibliográficos
Autores principales: Magnuson, Brian, Veloso, Artur, Kirkconnell, Killeen S., Lima, Leonardo Carmo de Andrade, Paulsen, Michelle T., Ljungman, Emily A., Bedi, Karan, Prasad, Jayendra, Wilson, Thomas E., Ljungman, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675984/
https://www.ncbi.nlm.nih.gov/pubmed/26656874
http://dx.doi.org/10.1038/srep17978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675984/
https://www.ncbi.nlm.nih.gov/pubmed/26656874
http://dx.doi.org/10.1038/srep17978

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