Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy

Follistatin is an inhibitor of TGF-β superfamily ligands that repress skeletal muscle growth and promote muscle wasting. Accordingly, follistatin has emerged as a potential therapeutic to ameliorate the deleterious effects of muscle atrophy. However, it remains unclear whether the anabolic effects o...

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Detalles Bibliográficos
Autores principales: Sepulveda, Patricio V., Lamon, Séverine, Hagg, Adam, Thomson, Rachel E., Winbanks, Catherine E., Qian, Hongwei, Bruce, Clinton R., Russell, Aaron P., Gregorevic, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675991/
https://www.ncbi.nlm.nih.gov/pubmed/26657343
http://dx.doi.org/10.1038/srep17535

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