Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells

Tumor Treating Fields (TTFields) are low intensity, intermediate frequency, alternating electric fields. TTFields are a unique anti-mitotic treatment modality delivered in a continuous, noninvasive manner to the region of a tumor. It was previously postulated that by exerting directional forces on h...

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Detalles Bibliográficos
Autores principales: Giladi, Moshe, Schneiderman, Rosa S, Voloshin, Tali, Porat, Yaara, Munster, Mijal, Blat, Roni, Sherbo, Shay, Bomzon, Zeev, Urman, Noa, Itzhaki, Aviran, Cahal, Shay, Shteingauz, Anna, Chaudhry, Aafia, Kirson, Eilon D, Weinberg, Uri, Palti, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676010/
https://www.ncbi.nlm.nih.gov/pubmed/26658786
http://dx.doi.org/10.1038/srep18046

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