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Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells

Chinese hamster ovary (CHO) cells are widely used as cell factories for the production of biopharmaceuticals. In contrast to the highly optimized production processes for monoclonal antibody (mAb)-based biopharmaceuticals, improving productivity of non-mAb therapeutic glycoproteins is more likely to...

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Detalles Bibliográficos
Autores principales: Hansen, Henning Gram, Nilsson, Claes Nymand, Lund, Anne Mathilde, Kol, Stefan, Grav, Lise Marie, Lundqvist, Magnus, Rockberg, Johan, Lee, Gyun Min, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676018/
https://www.ncbi.nlm.nih.gov/pubmed/26657798
http://dx.doi.org/10.1038/srep18016