Cargando…
Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells
Chinese hamster ovary (CHO) cells are widely used as cell factories for the production of biopharmaceuticals. In contrast to the highly optimized production processes for monoclonal antibody (mAb)-based biopharmaceuticals, improving productivity of non-mAb therapeutic glycoproteins is more likely to...
Autores principales: | Hansen, Henning Gram, Nilsson, Claes Nymand, Lund, Anne Mathilde, Kol, Stefan, Grav, Lise Marie, Lundqvist, Magnus, Rockberg, Johan, Lee, Gyun Min, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676018/ https://www.ncbi.nlm.nih.gov/pubmed/26657798 http://dx.doi.org/10.1038/srep18016 |
Ejemplares similares
-
A Versatile System for USER Cloning-Based Assembly of Expression Vectors for Mammalian Cell Engineering
por: Lund, Anne Mathilde, et al.
Publicado: (2014) -
Multi‐omic profiling of EPO‐producing Chinese hamster ovary cell panel reveals metabolic adaptation to heterologous protein production
por: Ley, Daniel, et al.
Publicado: (2015) -
Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data
por: Lund, Anne Mathilde, et al.
Publicado: (2017) -
A pooled CRISPR/AsCpf1 screen using paired gRNAs to induce genomic deletions in Chinese hamster ovary cells
por: Schmieder, Valerie, et al.
Publicado: (2021) -
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
por: Kallehauge, Thomas Beuchert, et al.
Publicado: (2017)