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Fancb deficiency impairs hematopoietic stem cell function
Fanconi anemia (FA) is a genetic disorder characterized by bone marrow failure, variable congenital malformations and a predisposition to malignancies. FANCB (also known as FAAP95), is the only X-linked FA gene discovered thus far. In the present study, we investigated hematopoiesis in adult Fancb d...
Autores principales: | Du, Wei, Amarachintha, Surya, Erden, Ozlem, Wilson, Andrew, Meetei, Amom Ruhikanta, Andreassen, Paul R., Namekawa, Satoshi H., Pang, Qishen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676042/ https://www.ncbi.nlm.nih.gov/pubmed/26658157 http://dx.doi.org/10.1038/srep18127 |
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