A dual role of transient receptor potential melastatin 2 channel in cytotoxicity induced by silica nanoparticles

Silica nanoparticles (NPs) have remarkable applications. However, accumulating evidence suggests NPs can cause cellular toxicity by inducing ROS production and increasing intracellular Ca(2+) ([Ca(2+)](i)), but the underlying molecular mechanism is largely unknown. Transient receptor potential melas...

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Detalles Bibliográficos
Autores principales: Yu, Peilin, Li, Jin, Jiang, Jialin, Zhao, Zunquan, Hui, Zhaoyuan, Zhang, Jun, Zheng, Yifan, Ling, Daishun, Wang, Lie, Jiang, Lin-Hua, Luo, Jianhong, Zhu, Xinqiang, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676061/
https://www.ncbi.nlm.nih.gov/pubmed/26656285
http://dx.doi.org/10.1038/srep18171

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