Association of elevated α-defensin levels with interstitial pneumonia in patients with systemic sclerosis

BACKGROUND: Interstitial lung disease (ILD) is the leading cause of mortality in patients with systemic sclerosis (SSc). Although the pathogenesis of SSc-ILD is not well understood, neutrophils may play a pivotal role in this process. Neutrophils store azurophil granules that contain defensins, anti...

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Detalles Bibliográficos
Autores principales: Sakamoto, Noriho, Kakugawa, Tomoyuki, Hara, Atsuko, Nakashima, Shota, Yura, Hirokazu, Harada, Tatsuhiko, Ishimoto, Hiroshi, Yatera, Kazuhiro, Kuwatsuka, Yutaka, Hara, Toshihide, Ichinose, Kunihiro, Obase, Yasushi, Ishimatsu, Yuji, Kohno, Shigeru, Mukae, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676113/
https://www.ncbi.nlm.nih.gov/pubmed/26654954
http://dx.doi.org/10.1186/s12931-015-0308-1

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