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Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach

BACKGROUND: The HIV-1 infection is characterized by profound CD4(+) T cell destruction and a marked Th17 dysfunction at the mucosal level. Viral suppressive antiretroviral therapy restores Th1 but not Th17 cells. Although several key HIV dependency factors (HDF) were identified in the past years via...

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Detalles Bibliográficos
Autores principales:	Cleret-Buhot, Aurélie, Zhang, Yuwei, Planas, Delphine, Goulet, Jean-Philippe, Monteiro, Patricia, Gosselin, Annie, Wacleche, Vanessa Sue, Tremblay, Cécile L., Jenabian, Mohammad-Ali, Routy, Jean-Pierre, El-Far, Mohamed, Chomont, Nicolas, Haddad, Elias K., Sekaly, Rafick-Pierre, Ancuta, Petronela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676116/ https://www.ncbi.nlm.nih.gov/pubmed/26654242 http://dx.doi.org/10.1186/s12977-015-0226-9

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