Cargando…

WNT5A transforms intestinal CD8αα(+) IELs into an unconventional phenotype with pro-inflammatory features

BACKGROUND: Intestinal intraepithelial lymphocytes that reside within the epithelium of the intestine form one of the main branches of the immune system. A majority of IELs express CD8α homodimer together with other molecules associated with immune regulation. Growing evidence points to the WNT sign...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Di, Xu, Antao, Dai, Zhanghan, Peng, Jiangchen, Zhu, Mingming, Shen, Jun, Zheng, Qing, Ran, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676129/
https://www.ncbi.nlm.nih.gov/pubmed/26652024
http://dx.doi.org/10.1186/s12876-015-0402-3