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WNT5A transforms intestinal CD8αα(+) IELs into an unconventional phenotype with pro-inflammatory features
BACKGROUND: Intestinal intraepithelial lymphocytes that reside within the epithelium of the intestine form one of the main branches of the immune system. A majority of IELs express CD8α homodimer together with other molecules associated with immune regulation. Growing evidence points to the WNT sign...
Autores principales: | Zhao, Di, Xu, Antao, Dai, Zhanghan, Peng, Jiangchen, Zhu, Mingming, Shen, Jun, Zheng, Qing, Ran, Zhihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676129/ https://www.ncbi.nlm.nih.gov/pubmed/26652024 http://dx.doi.org/10.1186/s12876-015-0402-3 |
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