Evidence that a neutrophil–keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis

The response of psoriasis to antibodies targeting the interleukin (IL)-23/IL-17A pathway suggests a prominent role of T-helper type-17 (Th17) cells in this disease. We examined the clinical and immunological response patterns of 100 subjects with moderate-to-severe psoriasis receiving 3 different in...

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Detalles Bibliográficos
Autores principales: Reich, Kristian, Papp, Kim A, Matheson, Robert T, Tu, John H, Bissonnette, Robert, Bourcier, Marc, Gratton, David, Kunynetz, Rodion A, Poulin, Yves, Rosoph, Les A, Stingl, Georg, Bauer, Wolfgang M, Salter, Janeen M, Falk, Thomas M, Blödorn-Schlicht, Norbert A, Hueber, Wolfgang, Sommer, Ulrike, Schumacher, Martin M, Peters, Thomas, Kriehuber, Ernst, Lee, David M, Wieczorek, Grazyna A, Kolbinger, Frank, Bleul, Conrad C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676308/
https://www.ncbi.nlm.nih.gov/pubmed/25828362
http://dx.doi.org/10.1111/exd.12710

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