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Contractile activity is required for Z-disc sarcomere maturation in vivo

Sarcomere structure underpins structural integrity, signaling, and force transmission in the muscle. In embryos of the frog Xenopus tropicalis, muscle contraction begins even while sarcomerogenesis is ongoing. To determine whether contractile activity plays a role in sarcomere formation in vivo, che...

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Detalles Bibliográficos
Autores principales: Geach, Timothy J, Hirst, Elizabeth MA, Zimmerman, Lyle B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676352/
https://www.ncbi.nlm.nih.gov/pubmed/25845369
http://dx.doi.org/10.1002/dvg.22851