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Spinal antinociceptive action of amiloride and its interaction with tizanidine in the rat formalin test
BACKGROUND: Amiloride has been reported to produce a wide variety of actions, thereby affecting several ionic channels and a multitude of receptors and enzymes. Intrathecal α(2)-adrenergic receptor agonists produce pronounced analgesia, and amiloride modulates α(2)-adrenergic receptor agonist bindin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pulsus Group Inc
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676503/ https://www.ncbi.nlm.nih.gov/pubmed/26357686 |