Spinal antinociceptive action of amiloride and its interaction with tizanidine in the rat formalin test

BACKGROUND: Amiloride has been reported to produce a wide variety of actions, thereby affecting several ionic channels and a multitude of receptors and enzymes. Intrathecal α(2)-adrenergic receptor agonists produce pronounced analgesia, and amiloride modulates α(2)-adrenergic receptor agonist bindin...

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Detalles Bibliográficos
Autores principales: Ouyang, Handong, Wang, Peizong, Huang, Wan, Li, Qiang, Nie, Bilin, Zeng, Weian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pulsus Group Inc 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676503/
https://www.ncbi.nlm.nih.gov/pubmed/26357686

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