Effect of oral N-acetylcysteine on COPD patients with microsatellite polymorphism in the heme oxygenase-1 gene promoter

BACKGROUND: Heme oxygenase-1 (HO-1) plays a protective role as an antioxidant in the lung, and HO-1 gene promoter polymorphism has been shown to be associated with the severity and prognosis of COPD patients. N-acetylcysteine (NAC), an antioxidant/mucous modifier, has shown an uncertain benefit in C...

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Qiang, Zhang, Jian-Qing, Fang, Li-Zhou, Liu, Ling, Fu, Wei-Ping, Dai, Lu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676509/
https://www.ncbi.nlm.nih.gov/pubmed/26674585
http://dx.doi.org/10.2147/DDDT.S91823

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