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Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants

Therapeutic performance of recombinant antibodies relies on two independent mechanisms: antigen recognition and Fc-mediated antibody effector functions. Interaction of Fc-fragment with different FcR triggers antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity and determine...

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Detalles Bibliográficos
Autores principales:	Dashivets, Tetyana, Thomann, Marco, Rueger, Petra, Knaupp, Alexander, Buchner, Johannes, Schlothauer, Tilman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676693/ https://www.ncbi.nlm.nih.gov/pubmed/26657484 http://dx.doi.org/10.1371/journal.pone.0143520

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