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Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats
BACKGROUND: Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease characterized by cellular infiltration into the joints, hyperproliferation of synovial cells and bone damage. Available treatments for RA only induce remission in around 30% of the patients, have important advers...
Autores principales: | Cascão, Rita, Vidal, Bruno, Lopes, Inês P., Paisana, Eunice, Rino, José, Moita, Luis F., Fonseca, João E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676706/ https://www.ncbi.nlm.nih.gov/pubmed/26658436 http://dx.doi.org/10.1371/journal.pone.0142448 |
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