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Arsenic trioxide reduces chemo-resistance to 5-fluorouracil and cisplatin in HBx-HepG2 cells via complex mechanisms

BACKGROUND: Multidrug resistance is one of the major reasons chemotherapy-based treatments failed in hepatitis B virus (HBV) related hepatocellular carcinoma (HCC). Hypoxia is generally associated with tumor chemo-resistance. The aim of the study was to investigate the effect of Arsenic trioxide (As...

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Detalles Bibliográficos
Autores principales:	Yu, Guifang, Chen, Xuezhu, Chen, Shudi, Ye, Weipeng, Hou, Kailian, Liang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676851/ https://www.ncbi.nlm.nih.gov/pubmed/26692822 http://dx.doi.org/10.1186/s12935-015-0269-y

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