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Unusual onset of a case of chronic recurrent multifocal osteomyelitis

BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition that commonly affects the clavicle and pelvis. CASE PRESENTATION: We report here a case a 12 years old girl with CRMO arising with recurrent episodes of left supraorbital headache, followed by the appearance of a perio...

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Autores principales: Barrani, M., Massei, F., Scaglione, M., Paolicchi, A., Vitali, S., Ciancia, E. M., Crovella, S., Caparello, M. C., Consolini, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676857/
https://www.ncbi.nlm.nih.gov/pubmed/26653878
http://dx.doi.org/10.1186/s12969-015-0058-0
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author Barrani, M.
Massei, F.
Scaglione, M.
Paolicchi, A.
Vitali, S.
Ciancia, E. M.
Crovella, S.
Caparello, M. C.
Consolini, R.
author_facet Barrani, M.
Massei, F.
Scaglione, M.
Paolicchi, A.
Vitali, S.
Ciancia, E. M.
Crovella, S.
Caparello, M. C.
Consolini, R.
author_sort Barrani, M.
collection PubMed
description BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition that commonly affects the clavicle and pelvis. CASE PRESENTATION: We report here a case a 12 years old girl with CRMO arising with recurrent episodes of left supraorbital headache, followed by the appearance of a periorbital dyschromia. Magnetic resonance imaging (MRI) of the skull and orbits revealed an important subacute inflammatory process. Few months after, the child presented a painful swelling of the left clavicle; the histological examination of the related biopsy allowed to establish the diagnosis of CRMO. CONCLUSION: CRMO presenting as acute headache involving neurocranium is rare; to our knowledge this is the first recognized case in the world literature. This pathological condition is frequently misdiagnosed as infection or neoplasm and needs a deep investigation for the differential diagnosis. The physical, laboratoristic and instrumental diagnostic investigations of the patient and the treatment employed are described in detail.
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spelling pubmed-46768572015-12-13 Unusual onset of a case of chronic recurrent multifocal osteomyelitis Barrani, M. Massei, F. Scaglione, M. Paolicchi, A. Vitali, S. Ciancia, E. M. Crovella, S. Caparello, M. C. Consolini, R. Pediatr Rheumatol Online J Case Report BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition that commonly affects the clavicle and pelvis. CASE PRESENTATION: We report here a case a 12 years old girl with CRMO arising with recurrent episodes of left supraorbital headache, followed by the appearance of a periorbital dyschromia. Magnetic resonance imaging (MRI) of the skull and orbits revealed an important subacute inflammatory process. Few months after, the child presented a painful swelling of the left clavicle; the histological examination of the related biopsy allowed to establish the diagnosis of CRMO. CONCLUSION: CRMO presenting as acute headache involving neurocranium is rare; to our knowledge this is the first recognized case in the world literature. This pathological condition is frequently misdiagnosed as infection or neoplasm and needs a deep investigation for the differential diagnosis. The physical, laboratoristic and instrumental diagnostic investigations of the patient and the treatment employed are described in detail. BioMed Central 2015-12-12 /pmc/articles/PMC4676857/ /pubmed/26653878 http://dx.doi.org/10.1186/s12969-015-0058-0 Text en © Barrani et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Barrani, M.
Massei, F.
Scaglione, M.
Paolicchi, A.
Vitali, S.
Ciancia, E. M.
Crovella, S.
Caparello, M. C.
Consolini, R.
Unusual onset of a case of chronic recurrent multifocal osteomyelitis
title Unusual onset of a case of chronic recurrent multifocal osteomyelitis
title_full Unusual onset of a case of chronic recurrent multifocal osteomyelitis
title_fullStr Unusual onset of a case of chronic recurrent multifocal osteomyelitis
title_full_unstemmed Unusual onset of a case of chronic recurrent multifocal osteomyelitis
title_short Unusual onset of a case of chronic recurrent multifocal osteomyelitis
title_sort unusual onset of a case of chronic recurrent multifocal osteomyelitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676857/
https://www.ncbi.nlm.nih.gov/pubmed/26653878
http://dx.doi.org/10.1186/s12969-015-0058-0
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