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The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment
BACKGROUND: Adequate expansion is critical to achieve optimal Bioresorbable Vascular Scaffolds (BVS) apposition to the vessel wall. However, compared to metallic stents, BVS present different mechanical properties. Hence, slow deployment and maintenance of balloon inflation for at least 30” is recom...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676860/ https://www.ncbi.nlm.nih.gov/pubmed/26654975 http://dx.doi.org/10.1186/s12872-015-0163-5 |
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author | Sorrentino, Sabato De Rosa, Salvatore Ambrosio, Giuseppe Mongiardo, Annalisa Spaccarotella, Carmen Polimeni, Alberto Sabatino, Jolanda Torella, Daniele Caiazzo, Gianluca Indolfi, Ciro |
author_facet | Sorrentino, Sabato De Rosa, Salvatore Ambrosio, Giuseppe Mongiardo, Annalisa Spaccarotella, Carmen Polimeni, Alberto Sabatino, Jolanda Torella, Daniele Caiazzo, Gianluca Indolfi, Ciro |
author_sort | Sorrentino, Sabato |
collection | PubMed |
description | BACKGROUND: Adequate expansion is critical to achieve optimal Bioresorbable Vascular Scaffolds (BVS) apposition to the vessel wall. However, compared to metallic stents, BVS present different mechanical properties. Hence, slow deployment and maintenance of balloon inflation for at least 30” is recommended for BVS implantation. However, since no evidences are available demonstrating the superiority of a longer balloon dilatation time, the implantation technique is highly variable among different centers. METHODS: A total of 24 BVS-treated lesions were included in the present analysis. After BVS deployment at 12 atmosphere (ATM) the balloon was rapidly deflated and scaffold expansion was documented with an angiogram. The same balloon was then inflated again and kept at 12 ATM for 30”. Finally, a further angiogram was obtained to evaluate BVS expansion. Quantitative coronary angiography (QCA) was performed at each step. RESULTS: A significant increase of minimal luminal diameter (MLD)-to-reference scaffold diameter (RSD) ratio (MLD to RSD Ration, MR-Ratio) from 0.70 ± 0.10 after initial stent deployment to 0.79 ± 0.10 after the 30”-long balloon dilation was observed (p < 0.001). Of note, this result was consistent across all sub-segments, as well as across almost all lesion subgroups. A substantial reduction in the prevalence of residual stenosis from 29 % to 17 % was registered after the 30”-long dilation. CONCLUSIONS: Our results strongly support the maintenance of balloon inflation for at least 30” during BVS deployment to achieve optimal scaffold expansion and minimize the occurrence of residual stenosis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12872-015-0163-5) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4676860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-46768602015-12-13 The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment Sorrentino, Sabato De Rosa, Salvatore Ambrosio, Giuseppe Mongiardo, Annalisa Spaccarotella, Carmen Polimeni, Alberto Sabatino, Jolanda Torella, Daniele Caiazzo, Gianluca Indolfi, Ciro BMC Cardiovasc Disord Research Article BACKGROUND: Adequate expansion is critical to achieve optimal Bioresorbable Vascular Scaffolds (BVS) apposition to the vessel wall. However, compared to metallic stents, BVS present different mechanical properties. Hence, slow deployment and maintenance of balloon inflation for at least 30” is recommended for BVS implantation. However, since no evidences are available demonstrating the superiority of a longer balloon dilatation time, the implantation technique is highly variable among different centers. METHODS: A total of 24 BVS-treated lesions were included in the present analysis. After BVS deployment at 12 atmosphere (ATM) the balloon was rapidly deflated and scaffold expansion was documented with an angiogram. The same balloon was then inflated again and kept at 12 ATM for 30”. Finally, a further angiogram was obtained to evaluate BVS expansion. Quantitative coronary angiography (QCA) was performed at each step. RESULTS: A significant increase of minimal luminal diameter (MLD)-to-reference scaffold diameter (RSD) ratio (MLD to RSD Ration, MR-Ratio) from 0.70 ± 0.10 after initial stent deployment to 0.79 ± 0.10 after the 30”-long balloon dilation was observed (p < 0.001). Of note, this result was consistent across all sub-segments, as well as across almost all lesion subgroups. A substantial reduction in the prevalence of residual stenosis from 29 % to 17 % was registered after the 30”-long dilation. CONCLUSIONS: Our results strongly support the maintenance of balloon inflation for at least 30” during BVS deployment to achieve optimal scaffold expansion and minimize the occurrence of residual stenosis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12872-015-0163-5) contains supplementary material, which is available to authorized users. BioMed Central 2015-12-11 /pmc/articles/PMC4676860/ /pubmed/26654975 http://dx.doi.org/10.1186/s12872-015-0163-5 Text en © Sorrentino et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Sorrentino, Sabato De Rosa, Salvatore Ambrosio, Giuseppe Mongiardo, Annalisa Spaccarotella, Carmen Polimeni, Alberto Sabatino, Jolanda Torella, Daniele Caiazzo, Gianluca Indolfi, Ciro The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment |
title | The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment |
title_full | The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment |
title_fullStr | The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment |
title_full_unstemmed | The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment |
title_short | The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment |
title_sort | duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676860/ https://www.ncbi.nlm.nih.gov/pubmed/26654975 http://dx.doi.org/10.1186/s12872-015-0163-5 |
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