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Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions

BACKGROUND: Phenotypic variability among inbred littermates reared in controlled environments remains poorly understood. Metastable epialleles refer to loci that intrinsically behave in this way and a few examples have been described. They display differential methylation in association with differe...

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Detalles Bibliográficos
Autores principales: Oey, Harald, Isbel, Luke, Hickey, Peter, Ebaid, Basant, Whitelaw, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676890/
https://www.ncbi.nlm.nih.gov/pubmed/26692901
http://dx.doi.org/10.1186/s13072-015-0047-z