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Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis
Objective. To investigate the effect and mechanism of the exenatide on diabetic cardiomyopathy. Methods. Rats were divided into control group, diabetes group (D), diabetes treated with insulin (DI) group, and diabetes treat with exenatide (DE) group. We detected apoptosis rate by TUNEL, the adiponec...
Autores principales: | XiaoTian, Lei, QiNan, Wu, XiaGuang, Gan, WuQuan, Deng, Bing, Chen, ZiWen, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677202/ https://www.ncbi.nlm.nih.gov/pubmed/26759813 http://dx.doi.org/10.1155/2016/4219735 |
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