Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation

Previous studies have demonstrated that sigma-1 receptor plays important roles in the induction phase of rodent neuropathic pain; however, whether it is involved in bone cancer pain (BCP) and the underlying mechanisms remain elusive. The aim of this study was to examine the potential role of the spi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Shanshan, Wang, Chenchen, Han, Yuan, Song, Chao, Hu, Xueming, Liu, Yannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677253/
https://www.ncbi.nlm.nih.gov/pubmed/26696751
http://dx.doi.org/10.1155/2015/265056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677253/
https://www.ncbi.nlm.nih.gov/pubmed/26696751
http://dx.doi.org/10.1155/2015/265056

Ejemplares similares