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Gene silencing of TACE enhances plaque stability and improves vascular remodeling in a rabbit model of atherosclerosis

We aimed to test the hypothesis that gene silencing of tumor necrosis factor alpha converting enzyme (TACE) may attenuate lesion inflammation and positive vascular remodeling and enhance plaque stability in a rabbit model of atherosclerosis. Lentivirus-mediated TACE shRNA was injected into the abdom...

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Detalles Bibliográficos
Autores principales:	Zhao, Xueqiang, Kong, Jing, Zhao, Yuxia, Wang, Xuping, Bu, Peili, Zhang, Cheng, Zhang, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677302/ https://www.ncbi.nlm.nih.gov/pubmed/26655882 http://dx.doi.org/10.1038/srep17939

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