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Anomalous Dynamics of a Lipid Recognition Protein on a Membrane Surface

Pleckstrin homology (PH) domains are lipid-binding modules present in peripheral membrane proteins which interact with phosphatidyl-inositol phosphates (PIPs) in cell membranes. We use multiscale molecular dynamics simulations to characterize the localization and anomalous dynamics of the DAPP1 PH d...

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Detalles Bibliográficos
Autores principales: Yamamoto, Eiji, Kalli, Antreas C., Akimoto, Takuma, Yasuoka, Kenji, Sansom, Mark S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677404/
https://www.ncbi.nlm.nih.gov/pubmed/26657413
http://dx.doi.org/10.1038/srep18245