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Public health impact and cost-effectiveness of dairy products supplemented with vitamin D in prevention of osteoporotic fractures

BACKGROUND: Dietary sources of calcium and vitamin D are recommended as a first-line strategy in prevention of osteoporosis-related fractures but their public health and economic impact has never been studied. METHODS: We designed a population-based model to forecast the potential health outcomes an...

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Detalles Bibliográficos
Autores principales: Ethgen, Olivier, Hiligsmann, Mickaël, Burlet, Nansa, Reginster, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677432/
https://www.ncbi.nlm.nih.gov/pubmed/26668740
http://dx.doi.org/10.1186/s13690-015-0099-3
Descripción
Sumario:BACKGROUND: Dietary sources of calcium and vitamin D are recommended as a first-line strategy in prevention of osteoporosis-related fractures but their public health and economic impact has never been studied. METHODS: We designed a population-based model to forecast the potential health outcomes and medical effectiveness of the daily administration of dairy supplements containing 800 IU of vitamin D and 1 g of calcium in cohorts of subjects, from both genders, aged 50, 60, 70 and 80 years. Annual costs of dairy products were tested at €150, €250 and €350. RESULTS: In total, the daily intake of vitamin-D rich dairy products reduces by 30,376 and 16,105 events the number of osteoporotic fractures in women and men respectively and permits to gain 6605 and 6144 life-years, in women and men respectively. This intervention is cost-effective from 70 years on in the general population and from 60 years on in patients at increased risk of osteoporotic fractures. CONCLUSION: The recommendation to use dairy products as the preferred source of calcium and vitamin D in aging males and females is supported by public health and health economic analyses. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13690-015-0099-3) contains supplementary material, which is available to authorized users.