Expression profiling and functional analysis of Toll-like receptors in primary healthy human nasal epithelial cells shows no correlation and a refractory LPS response

BACKGROUND: Innate immune recognition via Toll-like receptors (TLRs) on barrier cells like epithelial cells has been shown to influence the regulation of local immune responses. Here we determine expression level variations and functionality of TLRs in nasal epithelial cells from healthy donors. MET...

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Detalles Bibliográficos
Autores principales: van Tongeren, J., Röschmann, K. I. L., Reinartz, S. M., Luiten, S., Fokkens, W. J., de Jong, E. C., van Drunen, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677436/
https://www.ncbi.nlm.nih.gov/pubmed/26668716
http://dx.doi.org/10.1186/s13601-015-0086-3

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