Cargando…
Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests
Injury criteria and risk curves are needed for anthropomorphic test devices (dummies) to assess injuries for improving human safety. The present state of knowledge is based on using injury outcomes and biomechanical metrics from post-mortem human subject (PMHS) and mechanical records from dummy test...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677537/ https://www.ncbi.nlm.nih.gov/pubmed/26697422 http://dx.doi.org/10.3389/fbioe.2015.00196 |
_version_ | 1782405340446326784 |
---|---|
author | Yoganandan, Narayan Banerjee, Anjishnu Pintar, Frank A. |
author_facet | Yoganandan, Narayan Banerjee, Anjishnu Pintar, Frank A. |
author_sort | Yoganandan, Narayan |
collection | PubMed |
description | Injury criteria and risk curves are needed for anthropomorphic test devices (dummies) to assess injuries for improving human safety. The present state of knowledge is based on using injury outcomes and biomechanical metrics from post-mortem human subject (PMHS) and mechanical records from dummy tests. Data from these models are combined to develop dummy injury assessment risk curves (IARCs)/dummy injury assessment risk values (IARVs). This simple substitution approach involves duplicating dummy metrics for PMHS tested under similar conditions and pairing with PMHS injury outcomes. It does not directly account for the age of each specimen tested in the PMHS group. Current substitution methods for injury risk assessments use age as a covariate and dummy metrics (e.g., accelerations) are not modified so that age can be directly included in the model. The age-infusion methodology presented in this perspective article accommodates for an annual rate factor that modifies the dummy injury risk assessment responses to account for the age of the PMHS that the injury data were based on. The annual rate factor is determined using human injury risk curves. The dummy metrics are modulated based on individual PMHS age and rate factor, thus “infusing” age into the dummy data. Using PMHS injuries and accelerations from side-impact experiments, matched-pair dummy tests, and logistic regression techniques, the methodology demonstrates the process of age-infusion to derive the IARCs and IARVs. |
format | Online Article Text |
id | pubmed-4677537 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-46775372015-12-22 Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests Yoganandan, Narayan Banerjee, Anjishnu Pintar, Frank A. Front Bioeng Biotechnol Bioengineering and Biotechnology Injury criteria and risk curves are needed for anthropomorphic test devices (dummies) to assess injuries for improving human safety. The present state of knowledge is based on using injury outcomes and biomechanical metrics from post-mortem human subject (PMHS) and mechanical records from dummy tests. Data from these models are combined to develop dummy injury assessment risk curves (IARCs)/dummy injury assessment risk values (IARVs). This simple substitution approach involves duplicating dummy metrics for PMHS tested under similar conditions and pairing with PMHS injury outcomes. It does not directly account for the age of each specimen tested in the PMHS group. Current substitution methods for injury risk assessments use age as a covariate and dummy metrics (e.g., accelerations) are not modified so that age can be directly included in the model. The age-infusion methodology presented in this perspective article accommodates for an annual rate factor that modifies the dummy injury risk assessment responses to account for the age of the PMHS that the injury data were based on. The annual rate factor is determined using human injury risk curves. The dummy metrics are modulated based on individual PMHS age and rate factor, thus “infusing” age into the dummy data. Using PMHS injuries and accelerations from side-impact experiments, matched-pair dummy tests, and logistic regression techniques, the methodology demonstrates the process of age-infusion to derive the IARCs and IARVs. Frontiers Media S.A. 2015-12-14 /pmc/articles/PMC4677537/ /pubmed/26697422 http://dx.doi.org/10.3389/fbioe.2015.00196 Text en Copyright © 2015 Yoganandan, Banerjee and Pintar. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Yoganandan, Narayan Banerjee, Anjishnu Pintar, Frank A. Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests |
title | Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests |
title_full | Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests |
title_fullStr | Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests |
title_full_unstemmed | Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests |
title_short | Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests |
title_sort | age-infusion approach to derive injury risk curves for dummies from human cadaver tests |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677537/ https://www.ncbi.nlm.nih.gov/pubmed/26697422 http://dx.doi.org/10.3389/fbioe.2015.00196 |
work_keys_str_mv | AT yoganandannarayan ageinfusionapproachtoderiveinjuryriskcurvesfordummiesfromhumancadavertests AT banerjeeanjishnu ageinfusionapproachtoderiveinjuryriskcurvesfordummiesfromhumancadavertests AT pintarfranka ageinfusionapproachtoderiveinjuryriskcurvesfordummiesfromhumancadavertests |