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Inhibition of heat-shock protein 90 sensitizes liver cancer stem-like cells to magnetic hyperthermia and enhances anti-tumor effect on hepatocellular carcinoma-burdened nude mice

PURPOSE: To explore the thermoresistance and expression of heat-shock protein 90 (HSP90) in magnetic hyperthermia-treated human liver cancer stem-like cells (LCSCs) and the effects of a heat-shock protein HSP90 inhibitor 17-allylamino-17-demethoxgeldanamycin (17-AAG) on hepatocellular carcinoma-burd...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Tang, Qiusha, Miao, Fengqin, An, Yanli, Li, Mengfei, Han, Yong, Wang, Xihui, Wang, Juan, Liu, Peidang, Chen, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677660/
https://www.ncbi.nlm.nih.gov/pubmed/26677324
http://dx.doi.org/10.2147/IJN.S93758