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Breast Volume Asymmetry Value, Ratio, and Cancer Risk
AIM: The aim of this study was to investigate the criteria for determining the cancer risk of the breast asymmetry by comparing breast volume asymmetry levels between healthy women and women with cancer. MATERIALS AND METHODS: Two hundred and one women with breast cancer (group 1) were compared with...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677797/ https://www.ncbi.nlm.nih.gov/pubmed/26691819 http://dx.doi.org/10.4137/BCBCR.S32789 |
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author | Kayar, Ragıp Çilengiroğlu, Özgül V. |
author_facet | Kayar, Ragıp Çilengiroğlu, Özgül V. |
author_sort | Kayar, Ragıp |
collection | PubMed |
description | AIM: The aim of this study was to investigate the criteria for determining the cancer risk of the breast asymmetry by comparing breast volume asymmetry levels between healthy women and women with cancer. MATERIALS AND METHODS: Two hundred and one women with breast cancer (group 1) were compared with 446 healthy women (group 2) who had no pathologic findings in breast sonography and mammograpy repeated with one-year interval. Data were evaluated retrospectively. Each breast volume was measured twice by Grossman-Roudner Discs. The mean value has been recorded. The amounts of volume difference between two breasts (asymmetry value) and the rates of the volume difference to the breast volume of the smaller side (asymmetry ratio) were compared in both groups. RESULTS: There was a statistically significant difference between two groups with regard to average age and body mass index (P < 0.01). This significance was decreased but not disappeared, when the comparison was made within the 40–69 age group (P > 0.01). The rate of cases with asymmetry value over 50 mL was significantly higher in the cancer group (P = 0.029). Unfortunately, it disappeared in the 40–69 age group (P = 0.201). The breast volume asymmetry ratio over 20% was significantly higher in the cancer group both in all ages and in the 40–69 age group (P < 0.01). Odds ratio was 2.18 in the entire (all) series and 2.01 in the 40–69 age group. Moreover, there was no significant difference with regard to the rate of tumor location between the smaller or larger side of breast. CONCLUSION: Our data show that there is a positive correlation between breast asymmetry ratio over 20% and breast cancer risk. These results need to be confirmed by prospective randomized controlled trials. |
format | Online Article Text |
id | pubmed-4677797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-46777972015-12-19 Breast Volume Asymmetry Value, Ratio, and Cancer Risk Kayar, Ragıp Çilengiroğlu, Özgül V. Breast Cancer (Auckl) Original Research AIM: The aim of this study was to investigate the criteria for determining the cancer risk of the breast asymmetry by comparing breast volume asymmetry levels between healthy women and women with cancer. MATERIALS AND METHODS: Two hundred and one women with breast cancer (group 1) were compared with 446 healthy women (group 2) who had no pathologic findings in breast sonography and mammograpy repeated with one-year interval. Data were evaluated retrospectively. Each breast volume was measured twice by Grossman-Roudner Discs. The mean value has been recorded. The amounts of volume difference between two breasts (asymmetry value) and the rates of the volume difference to the breast volume of the smaller side (asymmetry ratio) were compared in both groups. RESULTS: There was a statistically significant difference between two groups with regard to average age and body mass index (P < 0.01). This significance was decreased but not disappeared, when the comparison was made within the 40–69 age group (P > 0.01). The rate of cases with asymmetry value over 50 mL was significantly higher in the cancer group (P = 0.029). Unfortunately, it disappeared in the 40–69 age group (P = 0.201). The breast volume asymmetry ratio over 20% was significantly higher in the cancer group both in all ages and in the 40–69 age group (P < 0.01). Odds ratio was 2.18 in the entire (all) series and 2.01 in the 40–69 age group. Moreover, there was no significant difference with regard to the rate of tumor location between the smaller or larger side of breast. CONCLUSION: Our data show that there is a positive correlation between breast asymmetry ratio over 20% and breast cancer risk. These results need to be confirmed by prospective randomized controlled trials. Libertas Academica 2015-12-10 /pmc/articles/PMC4677797/ /pubmed/26691819 http://dx.doi.org/10.4137/BCBCR.S32789 Text en © 2015 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 license. |
spellingShingle | Original Research Kayar, Ragıp Çilengiroğlu, Özgül V. Breast Volume Asymmetry Value, Ratio, and Cancer Risk |
title | Breast Volume Asymmetry Value, Ratio, and Cancer Risk |
title_full | Breast Volume Asymmetry Value, Ratio, and Cancer Risk |
title_fullStr | Breast Volume Asymmetry Value, Ratio, and Cancer Risk |
title_full_unstemmed | Breast Volume Asymmetry Value, Ratio, and Cancer Risk |
title_short | Breast Volume Asymmetry Value, Ratio, and Cancer Risk |
title_sort | breast volume asymmetry value, ratio, and cancer risk |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677797/ https://www.ncbi.nlm.nih.gov/pubmed/26691819 http://dx.doi.org/10.4137/BCBCR.S32789 |
work_keys_str_mv | AT kayarragıp breastvolumeasymmetryvalueratioandcancerrisk AT cilengirogluozgulv breastvolumeasymmetryvalueratioandcancerrisk |