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Evolutionary cell biology: functional insight from “endless forms most beautiful”
In animal and fungal model organisms, the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level. However, the model organisms cell biologists generally use include only a tiny fraction of the true diversity of e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678011/ https://www.ncbi.nlm.nih.gov/pubmed/26668171 http://dx.doi.org/10.1091/mbc.E14-10-1433 |
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author | Richardson, Elisabeth Zerr, Kelly Tsaousis, Anastasios Dorrell, Richard G. Dacks, Joel B. |
author_facet | Richardson, Elisabeth Zerr, Kelly Tsaousis, Anastasios Dorrell, Richard G. Dacks, Joel B. |
author_sort | Richardson, Elisabeth |
collection | PubMed |
description | In animal and fungal model organisms, the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level. However, the model organisms cell biologists generally use include only a tiny fraction of the true diversity of eukaryotic cellular forms. The divergent cellular processes observed in these more distant lineages are still largely unknown in the general scientific community. Despite the relative obscurity of these organisms, comparative studies of them across eukaryotic diversity have had profound implications for our understanding of fundamental cell biology in all species and have revealed the evolution and origins of previously observed cellular processes. In this Perspective, we will discuss the complexity of cell biology found across the eukaryotic tree, and three specific examples of where studies of divergent cell biology have altered our understanding of key functional aspects of mitochondria, plastids, and membrane trafficking. |
format | Online Article Text |
id | pubmed-4678011 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The American Society for Cell Biology |
record_format | MEDLINE/PubMed |
spelling | pubmed-46780112016-03-01 Evolutionary cell biology: functional insight from “endless forms most beautiful” Richardson, Elisabeth Zerr, Kelly Tsaousis, Anastasios Dorrell, Richard G. Dacks, Joel B. Mol Biol Cell Perspectives In animal and fungal model organisms, the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level. However, the model organisms cell biologists generally use include only a tiny fraction of the true diversity of eukaryotic cellular forms. The divergent cellular processes observed in these more distant lineages are still largely unknown in the general scientific community. Despite the relative obscurity of these organisms, comparative studies of them across eukaryotic diversity have had profound implications for our understanding of fundamental cell biology in all species and have revealed the evolution and origins of previously observed cellular processes. In this Perspective, we will discuss the complexity of cell biology found across the eukaryotic tree, and three specific examples of where studies of divergent cell biology have altered our understanding of key functional aspects of mitochondria, plastids, and membrane trafficking. The American Society for Cell Biology 2015-12-15 /pmc/articles/PMC4678011/ /pubmed/26668171 http://dx.doi.org/10.1091/mbc.E14-10-1433 Text en © 2015 Richardson et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0). “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology. |
spellingShingle | Perspectives Richardson, Elisabeth Zerr, Kelly Tsaousis, Anastasios Dorrell, Richard G. Dacks, Joel B. Evolutionary cell biology: functional insight from “endless forms most beautiful” |
title | Evolutionary cell biology: functional insight from “endless forms most beautiful” |
title_full | Evolutionary cell biology: functional insight from “endless forms most beautiful” |
title_fullStr | Evolutionary cell biology: functional insight from “endless forms most beautiful” |
title_full_unstemmed | Evolutionary cell biology: functional insight from “endless forms most beautiful” |
title_short | Evolutionary cell biology: functional insight from “endless forms most beautiful” |
title_sort | evolutionary cell biology: functional insight from “endless forms most beautiful” |
topic | Perspectives |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678011/ https://www.ncbi.nlm.nih.gov/pubmed/26668171 http://dx.doi.org/10.1091/mbc.E14-10-1433 |
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