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Clinical Features of Miller-Fisher Syndrome in Pregnancy

Miller-Fisher syndrome (MFS) is recognized as a variant of Guillain-Barré syndrome (GBS). MFS is a rare disorder that is characterized by the acute onset of ophthalmoplegia, ataxia, and areflexia/hyporeflexia. MFS has a higher incidence in Asia, where the incidence is estimated to be 18%–26% of GBS...

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Autores principales: Ono, Masanori, Sato, Hideki, Shirahashi, Mayu, Tomioka, Noriko, Maeda, Julia, Watanabe, Keiko, Amagata, Tomoko, Ikeda, Toshiyuki, Yakubo, Kazumi, Fukuiya, Tatsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678060/
https://www.ncbi.nlm.nih.gov/pubmed/26697248
http://dx.doi.org/10.1155/2015/840680
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author Ono, Masanori
Sato, Hideki
Shirahashi, Mayu
Tomioka, Noriko
Maeda, Julia
Watanabe, Keiko
Amagata, Tomoko
Ikeda, Toshiyuki
Yakubo, Kazumi
Fukuiya, Tatsuro
author_facet Ono, Masanori
Sato, Hideki
Shirahashi, Mayu
Tomioka, Noriko
Maeda, Julia
Watanabe, Keiko
Amagata, Tomoko
Ikeda, Toshiyuki
Yakubo, Kazumi
Fukuiya, Tatsuro
author_sort Ono, Masanori
collection PubMed
description Miller-Fisher syndrome (MFS) is recognized as a variant of Guillain-Barré syndrome (GBS). MFS is a rare disorder that is characterized by the acute onset of ophthalmoplegia, ataxia, and areflexia/hyporeflexia. MFS has a higher incidence in Asia, where the incidence is estimated to be 18%–26% of GBS compared with 3%–5% in the West. The differential diagnosis of MFS includes Wernicke's encephalopathy (WE) which is characterized by a clinical triad (nystagmus and ophthalmoplegia, mental status changes, and ataxia), myasthenia gravis, and brainstem stroke. The association between MFS and pregnancy has not been reported previously. Here, we describe the clinical features of a pregnant woman in early pregnancy with MFS. This case highlights the fact that it is necessary to establish an accurate diagnosis based on the details from the patient's history on appropriate complementary testing in a pregnant patient with MFS.
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spelling pubmed-46780602015-12-22 Clinical Features of Miller-Fisher Syndrome in Pregnancy Ono, Masanori Sato, Hideki Shirahashi, Mayu Tomioka, Noriko Maeda, Julia Watanabe, Keiko Amagata, Tomoko Ikeda, Toshiyuki Yakubo, Kazumi Fukuiya, Tatsuro Case Rep Obstet Gynecol Case Report Miller-Fisher syndrome (MFS) is recognized as a variant of Guillain-Barré syndrome (GBS). MFS is a rare disorder that is characterized by the acute onset of ophthalmoplegia, ataxia, and areflexia/hyporeflexia. MFS has a higher incidence in Asia, where the incidence is estimated to be 18%–26% of GBS compared with 3%–5% in the West. The differential diagnosis of MFS includes Wernicke's encephalopathy (WE) which is characterized by a clinical triad (nystagmus and ophthalmoplegia, mental status changes, and ataxia), myasthenia gravis, and brainstem stroke. The association between MFS and pregnancy has not been reported previously. Here, we describe the clinical features of a pregnant woman in early pregnancy with MFS. This case highlights the fact that it is necessary to establish an accurate diagnosis based on the details from the patient's history on appropriate complementary testing in a pregnant patient with MFS. Hindawi Publishing Corporation 2015 2015-12-01 /pmc/articles/PMC4678060/ /pubmed/26697248 http://dx.doi.org/10.1155/2015/840680 Text en Copyright © 2015 Masanori Ono et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ono, Masanori
Sato, Hideki
Shirahashi, Mayu
Tomioka, Noriko
Maeda, Julia
Watanabe, Keiko
Amagata, Tomoko
Ikeda, Toshiyuki
Yakubo, Kazumi
Fukuiya, Tatsuro
Clinical Features of Miller-Fisher Syndrome in Pregnancy
title Clinical Features of Miller-Fisher Syndrome in Pregnancy
title_full Clinical Features of Miller-Fisher Syndrome in Pregnancy
title_fullStr Clinical Features of Miller-Fisher Syndrome in Pregnancy
title_full_unstemmed Clinical Features of Miller-Fisher Syndrome in Pregnancy
title_short Clinical Features of Miller-Fisher Syndrome in Pregnancy
title_sort clinical features of miller-fisher syndrome in pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678060/
https://www.ncbi.nlm.nih.gov/pubmed/26697248
http://dx.doi.org/10.1155/2015/840680
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