Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia

Managing the blast phase in chronic myeloid leukemia (CML) is challenging because limited data are available for elderly patients. The involvement of the central nervous system (CNS) increases the risk of a poor prognosis. Here, we present an elderly blast phase CML patient with suspected CNS involv...

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Autores principales: Atilla, Erden, Ataca, Pinar, Ozyurek, Elif, Erden, Ilhan, Gurman, Gunhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678072/
https://www.ncbi.nlm.nih.gov/pubmed/26697241
http://dx.doi.org/10.1155/2015/689423
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author Atilla, Erden
Ataca, Pinar
Ozyurek, Elif
Erden, Ilhan
Gurman, Gunhan
author_facet Atilla, Erden
Ataca, Pinar
Ozyurek, Elif
Erden, Ilhan
Gurman, Gunhan
author_sort Atilla, Erden
collection PubMed
description Managing the blast phase in chronic myeloid leukemia (CML) is challenging because limited data are available for elderly patients. The involvement of the central nervous system (CNS) increases the risk of a poor prognosis. Here, we present an elderly blast phase CML patient with suspected CNS involvement who was successfully treated with bosutinib.
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spelling pubmed-46780722015-12-22 Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia Atilla, Erden Ataca, Pinar Ozyurek, Elif Erden, Ilhan Gurman, Gunhan Case Rep Hematol Case Report Managing the blast phase in chronic myeloid leukemia (CML) is challenging because limited data are available for elderly patients. The involvement of the central nervous system (CNS) increases the risk of a poor prognosis. Here, we present an elderly blast phase CML patient with suspected CNS involvement who was successfully treated with bosutinib. Hindawi Publishing Corporation 2015 2015-12-01 /pmc/articles/PMC4678072/ /pubmed/26697241 http://dx.doi.org/10.1155/2015/689423 Text en Copyright © 2015 Erden Atilla et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Atilla, Erden
Ataca, Pinar
Ozyurek, Elif
Erden, Ilhan
Gurman, Gunhan
Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_full Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_fullStr Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_full_unstemmed Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_short Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_sort successful bosutinib experience in an elderly acute lymphoblastic leukemia patient with suspected central nervous system involvement transformed from chronic myeloid leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678072/
https://www.ncbi.nlm.nih.gov/pubmed/26697241
http://dx.doi.org/10.1155/2015/689423
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