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Pluripotent stem cells for disease modeling and drug screening: new perspectives for treatment of cystic fibrosis?
Despite continuous improvements in treating clinical symptoms and the identification of single compounds that effectively rescue some rare mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), associated lung and liver pathologies remain largely untreatable and no real breakth...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678132/ https://www.ncbi.nlm.nih.gov/pubmed/26666881 http://dx.doi.org/10.1186/s40348-015-0023-5 |