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KRAS mutant lung cancer: progress thus far on an elusive therapeutic target
The KRAS mutation remains the most common driver mutation in patients with non-small cell lung cancer (NSCLC) and confers a poor prognosis. Thus far, efforts to target this mutation over the last two decades have been unsuccessful. Over the past 5 years, many efforts to develop drugs that target the...
Autores principales: | Bhattacharya, Saveri, Socinski, Mark A., Burns, Timothy F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678136/ https://www.ncbi.nlm.nih.gov/pubmed/26668062 http://dx.doi.org/10.1186/s40169-015-0075-0 |
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