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Overexpression of mitochondrial Hsp75 protects neural stem cells against microglia-derived soluble factor-induced neurotoxicity by regulating mitochondrial permeability transition pore opening in vitro

Microglia (MG)-induced neurotoxicity, a major determinant of Alzheimer's disease, is closely related to the survival of neural stem cells (NSCs). Heat shock protein 75 (Hsp75) has been reported to exert protective effects against environmental stresses; however, whether or not it protects NSCs...

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Detalles Bibliográficos
Autores principales:	WANG, YAN, LIN, JIZONG, CHEN, QING-ZHUANG, ZHU, NING, JIANG, DE-QI, LI, MING-XING, WANG, YONG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678160/ https://www.ncbi.nlm.nih.gov/pubmed/26500047 http://dx.doi.org/10.3892/ijmm.2015.2380

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