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CCN1/Cyr61-PI3K/AKT signaling promotes retinal neovascularization in oxygen-induced retinopathy

Retinal neovascularization (RNV) is a characteristic pathological finding of retinopathy of prematurity (ROP). Cysteine-rich 61 [Cyr61, also known as CCN family member 1 (CCN1)] has been reported to mediate angiogenesis. The aim of the present study was to investigate the mechanisms of CCN1/Cyr61-ph...

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Detalles Bibliográficos
Autores principales: DI, YU, ZHANG, YIOU, NIE, QINGZHU, CHEN, XIAOLONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678165/
https://www.ncbi.nlm.nih.gov/pubmed/26459773
http://dx.doi.org/10.3892/ijmm.2015.2371