Mechanical Stress Changes the Complex Interplay Between HO-1, Inflammation and Fibrosis, During Excisional Wound Repair

Mechanical stress following surgery or injury can promote pathological wound healing and fibrosis, and lead to functional loss and esthetic problems. Splinted excisional wounds can be used as a model for inducing mechanical stress. The cytoprotective enzyme heme oxygenase-1 (HO-1) is thought to orch...

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Detalles Bibliográficos
Autores principales: Cremers, Niels A. J., Suttorp, Maarten, Gerritsen, Marlous M., Wong, Ronald J., van Run-van Breda, Coby, van Dam, Gooitzen M., Brouwer, Katrien M., Kuijpers-Jagtman, Anne Marie, Carels, Carine E. L., Lundvig, Ditte M. S., Wagener, Frank A. D. T. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678194/
https://www.ncbi.nlm.nih.gov/pubmed/26697429
http://dx.doi.org/10.3389/fmed.2015.00086

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