A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signal Transduction Pathways from Artificial Clinical Data

Detection of malfunctioning reactions or molecules from clinical data is essential for disease treatments. In order to find an alternative to the existing oversimplistic mathematical models, a kinetic model is developed in this work to infer the malfunctioning reactions/molecules by quantifying the...

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Detalles Bibliográficos
Autores principales: Li, Xianhua, Ribaudo, Nicholas, Huang, Zuyi (Jacky)
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678239/
https://www.ncbi.nlm.nih.gov/pubmed/26697484
http://dx.doi.org/10.1155/2015/415083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678239/
https://www.ncbi.nlm.nih.gov/pubmed/26697484
http://dx.doi.org/10.1155/2015/415083

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