Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors

Tertiary lymphoid organs (TLOs) emerge during nonresolving peripheral inflammation, but their impact on disease progression remains unknown. We have found in aged Apoe(−/−) mice that artery TLOs (ATLOs) controlled highly territorialized aorta T cell responses. ATLOs promoted T cell recruitment, prim...

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Detalles Bibliográficos
Autores principales: Hu, Desheng, Mohanta, Sarajo K., Yin, Changjun, Peng, Li, Ma, Zhe, Srikakulapu, Prasad, Grassia, Gianluca, MacRitchie, Neil, Dever, Gary, Gordon, Peter, Burton, Francis L., Ialenti, Armando, Sabir, Suleman R., McInnes, Iain B., Brewer, James M., Garside, Paul, Weber, Christian, Lehmann, Thomas, Teupser, Daniel, Habenicht, Livia, Beer, Michael, Grabner, Rolf, Maffia, Pasquale, Weih, Falk, Habenicht, Andreas J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678289/
https://www.ncbi.nlm.nih.gov/pubmed/26084025
http://dx.doi.org/10.1016/j.immuni.2015.05.015

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