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Direct Catalytic Asymmetric Doubly Vinylogous Michael Addition of α,β-Unsaturated γ-Butyrolactams to Dienones**

An asymmetric doubly vinylogous Michael addition (DVMA) of α,β-unsaturated γ-butyrolactams to sterically congested β-substituted cyclic dienones with high site-, diastereo-, and enantioselectivity has been achieved. An unprecedented DVMA/vinylogous Michael addition/isomerization cascade reaction aff...

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Detalles Bibliográficos
Autores principales:	Gu, Xiaodong, Guo, Tingting, Dai, Yuanyuan, Franchino, Allegra, Fei, Jie, Zou, Chuncheng, Dixon, Darren J, Ye, Jinxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678421/ https://www.ncbi.nlm.nih.gov/pubmed/26184079 http://dx.doi.org/10.1002/anie.201504276

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