Near complete response after single dose of nivolumab in patient with advanced heavily pre-treated KRAS mutant pulmonary adenocarcinoma

The programmed death 1 (PD-1) receptor is expressed by activated T-cells and engaged by ligands PD-L1 and PD-L2 normally expressed by infiltrating immune cells in response to viral infection. The PD-1/PD-L1 axis is a negative inhibitory pathway that down-regulates T-cells but is also used by tumors...

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Detalles Bibliográficos
Autores principales: Davar, Diwakar, Socinski, Mark A., Dacic, Sanja, Burns, Timothy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678465/
https://www.ncbi.nlm.nih.gov/pubmed/26673119
http://dx.doi.org/10.1186/s40164-015-0029-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678465/
https://www.ncbi.nlm.nih.gov/pubmed/26673119
http://dx.doi.org/10.1186/s40164-015-0029-7

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