Phosphorylation of murine SAMHD1 regulates its antiretroviral activity

BACKGROUND: Human SAMHD1 is a triphosphohydrolase that restricts the replication of retroviruses, retroelements and DNA viruses in noncycling cells. While modes of action have been extensively described for human SAMHD1, only little is known about the regulation of SAMHD1 in the mouse. Here, we char...

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Detalles Bibliográficos
Autores principales: Wittmann, Sabine, Behrendt, Rayk, Eissmann, Kristin, Volkmann, Bianca, Thomas, Dominique, Ebert, Thomas, Cribier, Alexandra, Benkirane, Monsef, Hornung, Veit, Bouzas, Nerea Ferreirós, Gramberg, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678485/
https://www.ncbi.nlm.nih.gov/pubmed/26667483
http://dx.doi.org/10.1186/s12977-015-0229-6

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