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The Structure of a Plant Tyrosinase from Walnut Leaves Reveals the Importance of “Substrate-Guiding Residues” for Enzymatic Specificity

Tyrosinases and catechol oxidases are members of the class of type III copper enzymes. While tyrosinases accept both mono- and o-diphenols as substrates, only the latter substrate is converted by catechol oxidases. Researchers have been working for decades to elucidate the monophenolase/diphenolase...

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Detalles Bibliográficos
Autores principales: Bijelic, Aleksandar, Pretzler, Matthias, Molitor, Christian, Zekiri, Florime, Rompel, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678486/
https://www.ncbi.nlm.nih.gov/pubmed/26473311
http://dx.doi.org/10.1002/anie.201506994