Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells

BACKGROUND: Previously, we have demonstrated that human ABCB5 is a full-sized ATP-binding cassette transporter that shares strong homology with ABCB1/P-glycoprotein. ABCB5-transfected cells showed resistance to taxanes and anthracyclines. Herein, we further screened ABCB5 substrates, and explored th...

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Detalles Bibliográficos
Autores principales: Kondo, Shingo, Hongama, Keita, Hanaya, Kengo, Yoshida, Ryota, Kawanobe, Takaaki, Katayama, Kazuhiro, Noguchi, Kohji, Sugimoto, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678490/
https://www.ncbi.nlm.nih.gov/pubmed/26666373
http://dx.doi.org/10.1186/s40360-015-0038-5

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